온라인강의

Natural Compounds for Prevention and Alleviation for Endometriosis and Enhancement of Fertility
강사명YoungJoo Lee 강의시간32분 강의개설일2025-12-10
온라인강의

강의소개

Korean red ginseng (KRG) is a natural product with anti-inflammatory and anti-carcinogenic effects and used for menopause symptoms. Endometriosis is a common and complex estrogen-dependent pelvic inflammatory disease affecting approximately 6-10 % of reproductive age women. It is caused by changes in the immune surveillance of the local peritoneal microenvironment. The local inflammatory microenvironment enhances lesion proliferation, invasion and angiogenesis and subsequent progression to persistent endometrial lesions which may cause pelvic pain and infertility. In the mouse model, KRG administration significantly inhibited ectopic endometriosis growth of induced endometriosis. KRG does not interfere with the estrogen hormone synthesis. In this presentation, I will report our recent findings suggesting that KRG may be a promising lead for the protection and alleviation of endometriosis. and other natural compounds for endometriosis and decidualization which may aid enhancing implantation .

강사소개

Dr. Lee is a Professeor in the department of Integrative Bioscience and Biotechnology, Sejong University in Seoul, Korea. Dr. Lee majored in Pharmacy at Seoul National University. She moved to US for her Ph.D in 1992 at University of Wisconsin-Madison, Department of Biochemistry. She studied transcription mechanism of estrogen receptor under the supervision from Dr. Jack Gorski who is one of the leading pioneers in developing the mechanism for cellular mechanism of estrogen receptor. As a postdoctoral training, she worked at Seoul National University and Harvard Medical School Dana-Farber Cancer Institute. Since 2000, Dr. Lee has been working at the Sejong University. She served as a Dean of the College of Bioscience from 2019-2022. She has been working on the mechanism of breast cancer and endocrine disrupting chemicals of its toxicity and exposures. She has been actively involved and worked on developing alternative chemicals of endocrine disrupting chemicals and assessing its toxicity. She has a deep interest in delineating mechanism of ginseng especially with the emphasis on menopause and its associated cellular mechanism. She worked on identifying the cellular targets and mode of action of ginsenosides targeting middle-aged women health disturbances. She has been serving at the Korean Society of Ginseng over from 2012 and now is a vice president